Yeah, but I have seen most often recommended is buy a new block when you buy your synth line. The idea being, wire rope can really chew up the pulley which then can chew up your new (rather expensive) synth line.
The same goes for the fairlead. An aluminum hawse is best. A steel hawse can rust and most often has sharp edges and the synth line can get caught in the rollers on a roller fairlead (although someone makes a delrin roller replacement for use with synth line).
The one thing I have been debating with my line is how to spool it. I have had people say spool it normal and other say spool it “sloppy�. The problem with spooling it normal (like wire rope) is that the synth line can actually squeeze between the wraps. I have had this happen already. Although it doesn’t cause any ill-effect with the rope, it causes it to jam when free spooling. It also deforms it a little which many have said (and tested) that it doesn’t cause any weakness in the line. My line is currently spooled “sloppy� but I have not had to pull anyone out with it yet.